Heterozygous missense mutations of ALPK1 in the cohort and overview of... | Download Scientific Diagram
Aug 15, 2018 - Studies from Dr. Feng Shao's laboratory reveal that ADP-heptose, a precursor sugar molecule in bacterial LPS biosynthesis is recognized by a novel immune receptor kinase ALPK1, which stimulates
ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder | Genetics in Medicine
ALPK1-TIFA | Metabolite sensors | InvivoGen
ADP-Heptose | L- isomer | InvivoGen
Frontiers | Alpk1 Sensitizes Pancreatic Beta Cells to Cytokine-Induced Apoptosis via Upregulating TNF-α Signaling Pathway
ALPK1 and TIFA dependent innate immune response triggered by the Helicobacter pylori type IV secretion system | bioRxiv
ALPK1-IN-1 | ALPK1 Inhibitor | MedChemExpress
In vitro kinase assay reveals ADP-heptose-dependent ALPK1 autophosphorylation and altered kinase activity of disease-associated ALPK1 mutants | Scientific Reports
Cancers | Free Full-Text | Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases
ALPK1 controls TIFA/TRAF6-dependent innate immunity against heptose-1,7-bisphosphate of gram-negative bacteria | PLOS Pathogens
ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder | Genetics in Medicine
ADP-heptose: a bacterial PAMP detected by the host sensor ALPK1 | SpringerLink
Cancers | Free Full-Text | Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases
ALPK1-IN-2 | ALPK1 Inhibitor | MedChemExpress
CRISPR–Cas9 screens identify an ALPK1–TIFA axis that mediates... | Download Scientific Diagram
Science News Highlights - Mechanism of gastric inflammation by Helicobacter pylori Helicobacter pylori's ADP-heptose binds to the kinase ALPK1 in gastric epithelial cells and directs activation of classical and alternative NF-κB pathways
ALPK1 controls TIFA/TRAF6-dependent innate immunity against heptose-1,7-bisphosphate of gram-negative bacteria | PLOS Pathogens
ADP-Heptose (D- & L-isomer)
KO-TIFA & KO-ALPK1 cells | InvivoGen
Increase in the expression of ALPK1 during epithelial differentiation... | Download Scientific Diagram
KO-TIFA & KO-ALPK1 cells | InvivoGen
