![Schematic diagram of transcriptional regulation and function of the... | Download Scientific Diagram Schematic diagram of transcriptional regulation and function of the... | Download Scientific Diagram](https://www.researchgate.net/publication/7879983/figure/fig5/AS:280887540371460@1443980216352/Schematic-diagram-of-transcriptional-regulation-and-function-of-the-BACE2-and-BACE1-gene.png)
Schematic diagram of transcriptional regulation and function of the... | Download Scientific Diagram
![Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies - Ghosh - 2019 - ChemMedChem - Wiley Online Library Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies - Ghosh - 2019 - ChemMedChem - Wiley Online Library](https://chemistry-europe.onlinelibrary.wiley.com/cms/asset/78c906ec-440b-4522-b9b9-b841b6884af0/cmdc201800725-toc-0001-m.jpg)
Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies - Ghosh - 2019 - ChemMedChem - Wiley Online Library
![BACE2, as a novel APP θ‐secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome - Sun - 2006 - The FASEB Journal - Wiley Online Library BACE2, as a novel APP θ‐secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome - Sun - 2006 - The FASEB Journal - Wiley Online Library](https://faseb.onlinelibrary.wiley.com/cms/asset/455b5f28-b55d-4080-91b9-7a3938ff8c5b/fsb2fj055632com-fig-0005-m.jpg)
BACE2, as a novel APP θ‐secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome - Sun - 2006 - The FASEB Journal - Wiley Online Library
![BACE2 beyond β‐processing of APP, its neuroprotective role in cerebrovascular endothelium - Sáez‐Valero - Journal of Neurochemistry - Wiley Online Library BACE2 beyond β‐processing of APP, its neuroprotective role in cerebrovascular endothelium - Sáez‐Valero - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/8964058f-01f7-41c2-b978-946235072735/jnc15940-fig-0001-m.jpg)
BACE2 beyond β‐processing of APP, its neuroprotective role in cerebrovascular endothelium - Sáez‐Valero - Journal of Neurochemistry - Wiley Online Library
![Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41598-019-45896-4/MediaObjects/41598_2019_45896_Fig1_HTML.png)
Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports
![Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-019-45896-4/MediaObjects/41598_2019_45896_Fig3_HTML.png)
Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports
![The structure of the bACE2-Rm and the molecular basis of the bACE2-Rm... | Download Scientific Diagram The structure of the bACE2-Rm and the molecular basis of the bACE2-Rm... | Download Scientific Diagram](https://www.researchgate.net/publication/347922742/figure/fig2/AS:986078139936775@1612110757960/The-structure-of-the-bACE2-Rm-and-the-molecular-basis-of-the-bACE2-Rm-dimer-A-Overall.jpg)
The structure of the bACE2-Rm and the molecular basis of the bACE2-Rm... | Download Scientific Diagram
![BACE2, a β-secretase homolog, cleaves at the β site and within the amyloid-β region of the amyloid-β precursor protein | PNAS BACE2, a β-secretase homolog, cleaves at the β site and within the amyloid-β region of the amyloid-β precursor protein | PNAS](https://www.pnas.org/cms/10.1073/pnas.160115697/asset/52b2f2bc-8a57-40a1-a749-9baef8aa13d3/assets/graphic/pq1601156005.jpeg)
BACE2, a β-secretase homolog, cleaves at the β site and within the amyloid-β region of the amyloid-β precursor protein | PNAS
![Schematic illustration of BACE1 and BACE2 structural organizations.... | Download Scientific Diagram Schematic illustration of BACE1 and BACE2 structural organizations.... | Download Scientific Diagram](https://www.researchgate.net/publication/316251802/figure/fig1/AS:484903209967616@1492621342483/Schematic-illustration-of-BACE1-and-BACE2-structural-organizations-Both-BACE1-and.png)
Schematic illustration of BACE1 and BACE2 structural organizations.... | Download Scientific Diagram
![Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions | ACS Chemical Neuroscience Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions | ACS Chemical Neuroscience](https://pubs.acs.org/cms/10.1021/acschemneuro.9b00348/asset/images/large/cn9b00348_0001.jpeg)
Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions | ACS Chemical Neuroscience
Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions | ACS Chemical Neuroscience
Therapeutic concept of memapsin 1 (BACE2) inhibition for treating type... | Download Scientific Diagram
![BACE2 deficiency impairs expression and function of endothelial nitric oxide synthase in brain endothelial cells - He - Journal of Neurochemistry - Wiley Online Library BACE2 deficiency impairs expression and function of endothelial nitric oxide synthase in brain endothelial cells - He - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/98168230-c5e3-4f4e-9860-570336197ce5/jnc15929-fig-0007-m.png)
BACE2 deficiency impairs expression and function of endothelial nitric oxide synthase in brain endothelial cells - He - Journal of Neurochemistry - Wiley Online Library
![RCSB PDB - 2EWY: Crystal structure of human BACE2 in complex with a hydroxyethylenamine transition-state inhibitor RCSB PDB - 2EWY: Crystal structure of human BACE2 in complex with a hydroxyethylenamine transition-state inhibitor](https://cdn.rcsb.org/images/structures/2ewy_assembly-1.jpeg)
RCSB PDB - 2EWY: Crystal structure of human BACE2 in complex with a hydroxyethylenamine transition-state inhibitor
![Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2 | Journal of Medicinal Chemistry Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2 | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/acs.jmedchem.0c01858/asset/images/medium/jm0c01858_0010.gif)
Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2 | Journal of Medicinal Chemistry
![Distant Insulin Signaling Regulates Vertebrate Pigmentation through the Sheddase Bace2 - ScienceDirect Distant Insulin Signaling Regulates Vertebrate Pigmentation through the Sheddase Bace2 - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1534580718303575-fx1.jpg)
Distant Insulin Signaling Regulates Vertebrate Pigmentation through the Sheddase Bace2 - ScienceDirect
![Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-019-45896-4/MediaObjects/41598_2019_45896_Fig2_HTML.png)
Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports
![A Structure-Based Discovery Platform for BACE2 and the Development of Selective BACE Inhibitors | ACS Chemical Neuroscience A Structure-Based Discovery Platform for BACE2 and the Development of Selective BACE Inhibitors | ACS Chemical Neuroscience](https://pubs.acs.org/cms/10.1021/acschemneuro.0c00629/asset/images/large/cn0c00629_0005.jpeg)
A Structure-Based Discovery Platform for BACE2 and the Development of Selective BACE Inhibitors | ACS Chemical Neuroscience
![BACE-2 Inhibitor | BACE 2 inhibitor | BACE2 Inhibitor 3l | BACE 2 Inhibitor 3l | BACE-2 Inhibitor 3l | CAS [1676107-08-6] | Axon 2957 | Axon Ligand™ with >99% purity available from stock from supplier Axon Medchem BACE-2 Inhibitor | BACE 2 inhibitor | BACE2 Inhibitor 3l | BACE 2 Inhibitor 3l | BACE-2 Inhibitor 3l | CAS [1676107-08-6] | Axon 2957 | Axon Ligand™ with >99% purity available from stock from supplier Axon Medchem](https://www.axonmedchem.com/media/catalog/product/cache/1/image/9df78eab33525d08d6e5fb8d27136e95/2/9/2957.gif)